Agaricus blazei murrill (ABM)

The almond mushroom – there is scarcely another mushroom that stabilises the immune system as effectively as ABM.

Agaricus blazei murrill (ABM) is also known as Agaricus brasiliensis or the almond mushroom. It belongs to the button mushroom family and is a so-called secondary decomposer.

This light or dark brown, sometimes also greyish mushroom occurs naturally in the rainforests of Brazil. ABM displays a traditional mushroom shape with caps of around 12 to 14 centimetres, white to dark brown lamellae and stalks 10 to 14 centimetres long and 1.5 to 5 centimetres thick, sometimes hollow on the inside.

It is a popular and excellent edible mushroom in its Brazilian homeland. It is even venerated as the “mushroom of God”.

Main areas of use in mycotherapy:

Agaricus blazei murrill (ABM) regulates the entire immune system, especially in cases of cancer and autoimmune diseases. The reason for this is that ABM has an exceptionally high content of very effective immunomodulators.

ABM contains many long-chain polysaccharides, the beta-glucans. Their complex chemical structure leads to an equally complex effect: for example, they stimulate a weakened immune system, prevent excessive immune reactions or regulate these.

The effectiveness of ABM has been proven especially in cases of cancer of the abdomen, intestine, lungs, pancreas, prostate and liver, as well as brain tumours.

The constituent substances of ABM have a cytotoxic effect on cancer cells, can induce the apoptosis of neoplastic cells and suppress neoangiogenesis.

If haematopoiesis disturbances are evident after chemotherapy or radiotherapy, ABM supports the regeneration of bone marrow. Exhaustion following an erythrocyte deficit or an increasing immune weakness due to a loss of leukocytes can thus be counteracted. Furthermore, with the help of Agaricus blazei murrill, spleen swelling as occurs in cases of leukaemia or lymphoma can be reduced. The general condition of cancer patients can therefore be significantly improved.

Among the mushrooms studied so far, ABM has the highest content of superoxide dismutase (SOD), catalase and tyrosinase. These enzymes also occur in the body, where they exert a strong antioxidant effect. Oxidative stress and free radicals can therefore be reduced by ABM.

ABM also supports the spleen in cleansing the blood and in its immune defence function. Like all adaptogens, it has a protective effect on the liver. There are also positive experience reports in cases of fibromyalgia, multiple sclerosis, Alzheimer’s, Parkinson’s and rheumatism. It can also have a beneficial influence on autoimmune diseases of the thyroid or of the pancreas (type 1 diabetes).

Effects proved by studies:

  • Activation of humoral immunity: increased immunoglobulin M is formed and transforms later into immunoglobulin G
  • Increase and differentiation of macrophages and monocytes. This activates T cells that stimulate the B cells to greater antibody production through messenger substances (cytokine IL-6).

Sources:

  • Nakajima A., Ishida T., Koga M., Takeuchi T., Mazda O.,Takeuchi M.: “Effect of hot water extract from Agaricus blazei Murill on antibody-producing cells in mice”; International Immunopharmacology 2 (2002) 1205-1211
  • Cornelius, C.: “Comparative Enzyme Analysis…”; MRLNewsletter July 2009
  • Prof. Dr. med. Ivo Bianchi: “Moderne Mykotherapie”; Hinckel Druck, 2008

Note: The described effects are based on taking mushroom powder made from the whole mushroom. Please consult your therapist before use.

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